Delivery Mechanisms for Large Molecule Drugs: Successes and failures of leading technologies

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Report Format:	PDF
Date Published:	Jan-09
Product Type:	Business Insights Report
Table of Contents:	View Table of Contents

Report Description Large molecule drug markets have emerged as a key contender for R&D investment where small molecule pipelines are seeing growing generic pressures and reduced new drug approvals. Biotechnology companies, with a strong pipeline presence of large molecule biologic drugs, have benefited from strengthened market positioning. However, with drug failure rates for this immature industry high existing large molecule delivery is focused on the established parenteral route. Emerging drug delivery technologies are looking to improve measures of safety, efficacy, convenience and compliance in both new and existing drug candidates and products. For marketed products reformulations with new delivery technologies will extend the period of patent protection. In chronic diseases where patient compliance surrounding dosing strategies and ease of administration are key, limitations on further market growth these new formulas will be key to boosting volume sales of large molecule products. In R&D pipelines novel application of delivery technologies will expose new methods to reformulate failed or discontinued drugs and mask their unfavorable effects, expanding the market of potential drug candidates.
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